Structure-based fragment screening is demonstrated to be a practical lead discovery method for a representative G-protein-coupled receptor
J Med Chem
.
2013 May 9;56(9):3444-5.
doi: 10.1021/jm400561w.
Epub 2013 Apr 24.
Author
Benjamin D Stevens
1
Affiliation
1
Cambridge Laboratories, Pfizer Worldwide Research and Development , 620 Memorial Drive, Cambridge, Massachusetts 02139, United States. Benjamin.stevens@pfizer.com
PMID:
23614494
DOI:
10.1021/jm400561w
No abstract available
MeSH terms
Drug Evaluation, Preclinical / methods*
Ligands
Receptors, G-Protein-Coupled / metabolism*
Substances
Ligands
Receptors, G-Protein-Coupled